In the News...

NIHFebruary 13, 2024 

Obesity disrupts mitochondria, reduces fat-burning

Scientists identified a protein that triggers changes in mitochondria that lead to reduced fat-burning to promote weight gain in mice fed a high-fat diet.

The findings may point to potential new avenues for treating or preventing obesity in people.

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UCSD Today – January 29, 2024 

How Obesity Dismantles Our Mitochondria

UC San Diego study reveals key mechanism behind obesity-related metabolic dysfunction

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Science Daily – February 6, 2020 

Two enzymes control liver damage in NASH

After identifying a molecular pathway that allows nonalcoholic steatohepatitis (NASH) to progress into liver cell death, researchers were able to use these pathways to halt further liver damage.

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Eureka Alert – July 5th, 2018 

Repurposed asthma drug shows blood sugar improvement among some diabetics

After 12 weeks of taking an anti-asthma drug, a subset of patients with type 2 diabetes showed a clinically significant reduction in blood glucose during a randomized, double blind, placebo-controlled clinical trial, report University of California San Diego School of Medicine and University of Michigan researchers.

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Science Daily – February 8th 2018

Enzyme plays a key role in calories burned both during obesity and dieting

Ever wonder why obese bodies burn less calories or why dieting often leads to a plateau in weight loss? In both cases the body is trying to defend its weight by regulating energy expenditure. In a new paper, researchers identify the enzyme TANK-binding kinase 1 (TBK1) as a key player in the control of energy expenditure during both obesity and fasting. 

More In the News...

Fierce Biotech – February 8th 2018

Fighting obesity by controlling inflammation

The San Diego Union Tribune - September 22nd 2016

How to battle cancer linked to obesity 

Science - October 10, 2014

New class of fatty molecules battles diabetes in mice

USA Today - July 1, 2013

Study: Canker sore drug made mice skinny